The driving distance is approximately 3880 to 3940 kilometers. This route involves significant border crossings (e.g., between Argentina, Bolivia, and Peru) and can present challenges due to diverse road conditions and high-altitude areas. Fuel costs are estimated based on an average consumption and current prices in Argentina (ARS 1,335-1,655 per liter / USD 0.87-1.14 per liter) and Peru (PEN 4.07-5.09 per liter / USD 1.10-1.21 per liter). Tolls are applicable in both Argentina and Peru, varying by route segment and vehicle type. It is strongly recommended to research border requirements, vehicle insurance, and road conditions in advance. Renting a car for a one-way international trip of this magnitude is generally not feasible from standard rental agencies.