The distance is approximately 730-886.5 miles (1175-1427 km). Major routes may include interstates like I-65 N, I-70 E, and I-79 N. Expect tolls, particularly on segments like the Pennsylvania Turnpike, Ohio Turnpike, and Indiana Toll Road. Fuel costs are estimates based on average prices and vehicle efficiency. Consider using a toll calculator for precise routing and cost estimates.