The distance is approximately 340-400 miles (545-649 km). The fastest route is typically via I-5, taking around 5.5 to 7 hours, largely dependent on traffic, especially around urban areas. A more scenic route, though longer (7-9 hours or more), is US-101 or parts of Highway 1 (Pacific Coast Highway), offering coastal views, particularly south of San Luis Obispo. Tolls are generally not encountered on the primary inter-city freeway routes (I-5, US-101) unless choosing specific express lanes or crossing Bay Area bridges not directly on the main highway toward Los Angeles. Fuel costs are estimates and vary based on vehicle efficiency and current gas prices.