The distance is approximately 416-446 km via the main Presidente Dutra Highway (BR-116), which is a well-maintained toll road. Expect multiple toll plazas. Electronic payment tags like Sem Parar or ConectCar can offer convenience and minor discounts. Traffic can be significant, especially near urban centers and during peak hours. An alternative, longer, but scenic coastal route (Rio-Santos Highway) is also an option for those seeking picturesque views.